Network‐Like Organization of the Circadian System Regulates Metabolic Homeostasis
نویسندگان
چکیده
منابع مشابه
Circadian clocks, feeding time, and metabolic homeostasis
Metabolic processes exhibit diurnal variation from cyanobacteria to humans. The circadian clock is thought to have evolved as a time keeping system for the cell to optimize the timing of metabolic events according to physiological needs and environmental conditions. Circadian rhythms temporally separate incompatible cellular processes and optimize cellular and organismal fitness. A modern 24 h ...
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15 صفحه اولCircadian regulation of metabolic homeostasis: causes and consequences
Robust circadian rhythms in metabolic processes have been described in both humans and animal models, at the whole body, individual organ, and even cellular level. Classically, these time-of-day-dependent rhythms have been considered secondary to fluctuations in energy/nutrient supply/demand associated with feeding/fasting and wake/sleep cycles. Renewed interest in this field has been fueled by...
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Circadian rhythms, metabolism, and nutrition are intimately linked [1, 2], although effects of meal timing on the human circadian system are poorly understood. We investigated the effect of a 5-hr delay in meals on markers of the human master clock and multiple peripheral circadian rhythms. Ten healthy young men undertook a 13-day laboratory protocol. Three meals (breakfast, lunch, dinner) were...
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ژورنال
عنوان ژورنال: Obesity
سال: 2020
ISSN: 1930-7381,1930-739X
DOI: 10.1002/oby.22773